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The only way to pick more advanced locks is to spend points on the Locksmith perk - ditto for unlocking computers and the Hacker perk.
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Instead, when you level up, you can choose to unlock certain perks.
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Unlike past Fallout titles, there is no separate collection of specific skills to spend points on.
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Your character is defined by SPECIAL: base stats representing Strength, Perception, Endurance, Charisma, Intelligence, Agility, and Luck that you choose at the beginning of the game.
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